News

From Research to Clinic: St. Anna CCRI’s Pharmacogenomics Symposium St. Anna CCRI hosted its first pharmacogenomics symposium, showcasing the intersection of science and clinical practice in precision oncology. Renowned speakers Dr. Mary Relling and Dr. William Evans explored the impact of genetic data on drug prescription and the importance of international guideline development, as well […]

Shining New Light on the Onset of Childhood Cancer  Cell mutations can occur during human embryonic development, potentially leading to childhood cancer such as neuroblastoma. Polina Kameneva, recently appointed as Principal Investigator at St. Anna Children’s Cancer Research Institute (St. Anna CCRI), is dedicated to investigating these critical phases. She employs mini-organ cultures and genetic

Polina Kameneva wins FWF Start Prize (21.06.2024) Yesterday, Polina Kameneva won the prestigious FWF START Prize for her innovative research project. In her project she aims to understand the protective mechanisms of cells at different stages of development, particularly with regard to neuroblastoma. The FWF START Prize provides researchers with a financial basis for carrying out long-term

Replacing animal testing for Langerhans cell histiocytosis Caroline Hutter’s group at St. Anna CCRI recently received a major grant from the FWF to develop advanced, animal-free therapeutic approaches for the treatment of Langerhans cell histiocytosis (LCH). This rare disease, caused by an excessive accumulation of langerin expressing cells, poses a major challenge, especially for young

Innovative stem cell model provides insight into childhood cancer origins Researchers from the University of Sheffield and St. Anna Children’s Cancer Research Institute have created a model designed to investigate the origins of neuroblastoma, a cancer primarily affecting infants and young children. The findings offer hope for the creation of tailored treatments which treat aggressive neuroblastomas

Eleni Tomazou takes up tenure-track assistant professorship at Medical University Vienna (Vienna, 03.05.24) At the beginning of May, Eleni Tomazou took up a §99.5 assistant professorship in sarcoma biology at the Medical University of Vienna. The scientist has been leading a research group on pediatric sarcomas at St. Anna Children’s Cancer Research Institute (CCRI) with great

Long Night of Research 2024: Working together in Childhood Cancer Research Join us on Friday, May 24th, from 5-11 p.m. and dive into the world of childhood cancer research! (Vienna, 29.04.24) The Long Night of Research 2024 is approaching and cordially invites you to explore the world of childhood cancer research under the motto “Innovation through

FWF’s ESPRIT Program supports Research on β-Catenin in Wilms Tumor  The Austrian Science Fund’s ESPRIT program has awarded funding to Maud Plaschka’s project focused on exploring β-catenin’s role in Wilms tumor, recognizing the need for innovative research in pediatric oncology. This initiative aims to determine the therapeutic potential of β-catenin inhibitors, addressing a significant gap

MSCA Postdoctoral Fellowship enables the building of fusion-driven Sarcoma Models Sarcomas, aggressive tumors that primarily affect children and adolescents, are the focus of a new project at St. Anna CCRI.  Despite advanced medicine, survival rates of patients with Sarcomas are low and treatment methods are outdated. Strengthened by a prestigious Marie Curie Postdoctoral Fellowship, Ornella Urzì is

When Acute Lymphoblastic Leukemia (ALL) Transforms (Vienna, 05.04.2024) Acute lymphoblastic leukemia (ALL) is highly treatable. However, for new treatment methods in personalized medicine, subtypes of this leukemia must be studied more thoroughly. A team of researchers from St. Anna Children’s Cancer Research Institute and the University of Padua has now made another step forward in

The two faces of neutrophils in tumor biology (Vienna, 26.03.2024) Neutrophils are the most common white blood cells and an important component of the immune system. They help in the defense against pathogens and in the healing of injuries. They are also suspected to play a role in tumor development. A team from St. Anna

Researchers investigate the control center for maintaining immune cell fitness  (Vienna, 14.03.2024) The endoplasmic reticulum in human immune cells is the topic of a current research project at the St. Anna Children’s Cancer Research Institute (CCRI). This highly complex network of membrane structures is where the cells proteins are produced and the quality control processes that

United Fight Against Osteosarcoma: Innovative T-Cell Therapy Research (Vienna, March 12, 2024) The St. Anna Children’s Cancer Research Institute is at the forefront of a groundbreaking research initiative targeting osteosarcoma, the most prevalent aggressive bone cancer in children and young adults. The project, DART2OS, spearheaded by the Institute of Molecular Pathology (IMP) and supported by the

International Women’s Day: Spotlight on the Power of Women  (Vienna, 8.3.2024) In celebration of International Women’s Day, we proudly highlight the incredible women of St. Anna Children’s Cancer Research Institute, where an inspiring 67% of our dedicated team members are women. Among them stand Principal Investigators Eleni Tomazou and Sabine Taschner-Mandl, whose contributions shape the landscape

Why Rare Disease Research Matters – Today is Rare Disease Day 2024 Today, on Rare Disease Day, we’re proud to release a special video featuring researchers from around the globe! Join us as they share why research into rare diseases is vital and how it can make a profound impact on countless lives. Together with the

St. Anna CCRI wants to develop new drug against Ewing sarcoma with international partners A three-year project aims to improve the long-term survival rate of patients with Ewing sarcoma. (Vienna, 22.02.2024) Ewing sarcoma is a very aggressive, rapidly metastasizing bone cancer. In Austria, five to eight children and adolescents are affected every year. The long-term