A Light Against Cancer A team of scientists at St. Anna Children’s Cancer Research Institute (St. Anna CCRI) has developed a method to eliminate cancer cells with precision, without harming healthy tissue. Using a light-activatable compound called SBTubA4P, they successfully destroyed tumor cells in an animal model. This promising discovery could one day offer a […]
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How collaboration drives innovation… with Florian Grebien Collaborations are essential in the world of science. In addition to the exchange of knowledge and technologies, they also offer valuable insights into different cultural and methodological approaches to research. This view is shared by Florian Grebien, Principal Investigator (PI) of the Biology of Pediatric Leukemia Oncoproteins research
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Women in Science: Researchers Shaping the Future Science thrives on curiosity, perseverance, and the passion to better understand the world. Yet, for many women, the path to a career in research has not always been straightforward. Stereotypes, structural barriers, and a lack of role models still discourage some girls from considering a future in science.
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Very Rare Subtype of Childhood Leukemia Characterized A team at the St. Anna Children’s Cancer Research Institute (St. Anna CCRI) has headed an international collaborative study to characterize a very rare subtype of childhood B-cell acute lymphoblastic leukemia. The results, recently published in the journal Leukemia show that patients with this subtype need optimized therapy.
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Epigenetics Brings Hope for New Therapies Epigenetics is a key area of pediatric cancer research. Scientists are investigating molecular drivers of tumors, hoping to discover new therapies through these approaches. St. Anna Children’s Cancer Research Institute (St. Anna CCRI) has long focused on epigenetics and recently hosted a networking meeting on the topic. Adult tumors
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Breakthrough in Langerhans Cell Histiocytosis Research: Stem Cell Model Paves the Way for New Therapies (Vienna, 16 December 2024) Scientists at St. Anna Children’s Cancer Research Institute (St. Anna CCRI) have achieved a milestone in the study of the rare and complex disease Langerhans Cell Histiocytosis (LCH). Using an innovative model based on induced pluripotent
‘Working together’ with Sabine Strehl In today’s biomedical research, interdisciplinary collaboration is essential. While leukemia is the most common childhood cancer, certain subtypes are extremely rare necessitating international studies for comprehensive data collection to understand their pathogenesis and prognostic relevance. Sabine Strehl’s research focuses on unraveling the genetic mechanisms behind leukemia development, emphasizing the importance
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Genetic Defect in Secondary Immune Organs Causes Life-Threatening Infections in Children (Vienna, November 22, 2024) An international team led by Kaan Boztug, MD has identified a new form of a rare disease that affects secondary lymphoid organs, shedding light on the significance of these structures for the human immune system. The discovered genetic defect leads
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Collaboration with Davide Seruggia In biomedicine, collaboration is more than a buzzword—it’s an essential component of advancing our understanding of complex diseases. As technology and scientific knowledge evolve, the scope of research has expanded to include numerous specialized fields, each bringing unique insights and tools. Consequently, biomedicine relies increasingly on interdisciplinary research groups, where scientists
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How to Combat Fungal Infections in Immunocompromised Patients? (Vienna, 17. 10. 2024) A new study from the St. Anna Children’s Cancer Research Institute (St. Anna CCRI) warns of the hidden dangers of invasive fungal infections in immunocompromised patients. The international research team, led by scientists Chantal Lucini, Klára Obrová, and Thomas Lion, has found that
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ESCCA Conference 2024: Advancements in Clinical Cell Analysis Margarita Maurer-Granofszky, researcher of the Dworzak group, was invited to present her research at the ESCCA Conference 2024. In her presentations, she highlighted the importance of detecting minimal/measurable residual disease (MRD) in children with acute myeloid leukemia (AML) and how new technologies like artificial intelligence (AI) can
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Student Applies AI in Cancer Detection and supports St. Anna CCRI (Vienna, 21.08.2024) Alessandro Rodias, a student from the Sir Karl Popper School in Vienna has explored the potential of radiomics in cancer detection. Through his innovative project, he has demonstrated how artificial intelligence (AI) can be applied to analyze radiological images for improved cancer diagnosis.
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New Insights into Risk Factors for a Subtype of Acute Lymphoblastic Leukemia A team around Sabine Strehl and Dagmar Schinnerl has made significant progress in studying a subtype of B-cell acute lymphoblastic leukemia. The research findings, recently published in the Blood Cancer Journal, shed new light on the specific characteristics and risk factors of this
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Resistance is Futile: DOC Fellowship for Cancer Resistance Research Leonie Lehmayer, a dedicated early-career researcher at St. Anna Children’s Cancer Research Institute, has recently been awarded a prestigious DOC Fellowship from the Austrian Academy of Sciences. Her PhD project focuses on studying enhancers and their role in drug resistance and relapse in cancer patients. Many
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From Research to Clinic: St. Anna CCRI’s Pharmacogenomics Symposium St. Anna CCRI hosted its first pharmacogenomics symposium, showcasing the intersection of science and clinical practice in precision oncology. Renowned speakers Dr. Mary Relling and Dr. William Evans explored the impact of genetic data on drug prescription and the importance of international guideline development, as well
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Shining New Light on the Onset of Childhood Cancer Cell mutations can occur during human embryonic development, potentially leading to childhood cancer such as neuroblastoma. Polina Kameneva, recently appointed as Principal Investigator at St. Anna Children’s Cancer Research Institute (St. Anna CCRI), is dedicated to investigating these critical phases. She employs mini-organ cultures and genetic
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