National & International Grants

Nationally Funded Projects

It is contracting: Physics meets Ewing sarcoma biology
CCRI responsible Principal Investigator: Eleni Tomazou
Grant from the Austrian Science Fund (FWF), 1000 Ideas (TAI)
DOI: 10.55776/ TAI1842825
Duration: 01/01/2026 – 31/12/2027
https://www.fwf.ac.at/en/research-radar/10.55776/TAI1842825

Functional identification and targeting of zinc-finger containing proteins on domain resolution in leukemia
CCRI responsible researcher and Awardee: Christina Horstmann (Supervisor: Florian Grebien)
Grant from the Austrian Academy of Sciences (ÖAW), DOC fellowship, ID – 27406
Duration: 01/01/2026 – 31/12/2027
https://stipendien.oeaw.ac.at/en/stipendien/doc/doc-gefoerderte-personen

Resistance evolution in solid paediatric cancers with HRD (RECHORD)
CCRI responsible Principal Investigator: George Cresswell
Grant from the Austrian Science Fund (FWF), Principal Investigator Project (PAT)
DOI: 10.55776/PAT2727724
Duration: 01/11/2025 – 31/10/2029
https://www.fwf.ac.at/en/research-radar/10.55776/PAT2727724

Understanding the role of BRAFV600E in Langerhans Cell Histiocytosis (UnVEiL)
CCRI responsible Principal Investigator: Caroline Hutter
Grant from the Austrian Science Fund (FWF), Principal Investigator Project (PAT)
DOI: 10.55776/PAT6449724
Duration: 01/04/2025 – 31/03/2028
https://www.fwf.ac.at/en/research-radar/10.55776/PAT6449724

Improving tumor specificity of cellular immunotherapies
Head of CD Laboratory and CCRI responsible Project Lead: Manfred Lehner
Grant from the Austrian Science Fund (FWF), Principal Investigator Project (PAT)
DOI: 10.55776/PAT8789924
Duration: 01/11/2024 – 31/10/2028
https://www.fwf.ac.at/en/research-radar/10.55776/PAT8789924

EXPLORing the Epigenetic NeuroBlastoma landscape to improve measurable disease monitoring, disease understanding and personalized treatment (EXPLORE-NB)
CCRI responsible Principal Investigator: Sabine Taschner-Mandl
Grant from the Austrian Science Fund (FWF), International – Multilateral Initiatives
DOI: 10.55776/PIN2827223
Duration: 01/11/2024 – 31/10/2027
https://www.fwf.ac.at/en/research-radar/10.55776/PIN2827223

Single cell transcriptomics and epigenomics unravel the role of monocytes in neuroblastoma bone marrow metastasis
CCRI responsible Principal Investigator: Sabine Taschner-Mandl
Grant from the Austrian Society for Pediatrics and Adolescent Medicine (ÖGKJ) – 2024 Science Prize
Duration: 05/10/2024 – 31/12/2027

Modelling pediatric tumor initiation with human stem cells
CCRI responsible Principal Investigator and Awardee: Polina Kameneva
Grant from the Austrian Science Fund (FWF), START Award
DOI: 10.55776/STA193
Duration: 01/10/2024 – 30/09/2029
https://www.fwf.ac.at/en/research-radar/10.55776/STA193

Devising Advanced TCR-T cells to eradicate OsteoSarcoma (DART2OS)
CCRI responsible Principal Investigator: Sabine Taschner-Mandl
Coordinator: Johannes Zuber (IMP, Austria)
Grant from the Austrian Science Fund (FWF), Emerging Fields Program
DOI: 10.55776/EFP45
Duration: 01/10/2024 – 30/09/2029
https://www.fwf.ac.at/en/research-radar/10.55776/EFP45

Role of enhancers in non-mutational drug resistance and relapse
CCRI responsible researcher and Awardee: Leonie Lehmayer (Supervisor: Davide Seruggia)
Grant from the Austrian Academy of Sciences (ÖAW), DOC fellowship, ID – 27138
Duration: 01/09/2024 – 01/09/2026
https://stipendien.oeaw.ac.at/en/stipendien/doc/doc-gefoerderte-personen

ß-catenin Roles and Dynamics in Wilms Tumors
CCRI responsible Project Lead: Maud Plaschka (Florian Halbritter group)
Grant from the Austrian Science Fund (FWF), ESPRIT Program
DOI: 10.55776/ESP652
Duration: 01/09/2024 – 31/08/2027
https://www.fwf.ac.at/en/research-radar/10.55776/ESP652

Oncogenic aberration of development in childhood cancer
CCRI responsible Principal Investigator: Florian Halbritter
Grant from the Austrian Science Fund (FWF), Principal Investigator Project (PAT)
DOI: 10.55776/PAT1300223
Duration: 01/06/2024 – 31/05/2028
https://www.fwf.ac.at/en/research-radar/10.55776/PAT1300223

Human Induced Pluripotent Stem Cells as a preclinical trial platform for Langerhans Cell Histiocytosis (HIPSC-LCH)
CCRI responsible Principal Investigator: Caroline Hutter
Grant from the Austrian Science Fund (FWF), Principal Investigator Project (PAT)
DOI: 10.55776/P37332
Duration: 01/05/2024 – 30/04/2027
https://www.fwf.ac.at/en/research-radar/10.55776/P37332

New Hsp90 Inhibitor-based Therapies for Ewing Sarcoma (HSP90IES)
Head of Facility and CCRI responsible Project Lead: Caterina Sturtzel
Grant from the Austrian Science Fund (FWF), Principal Investigator Projects International
DOI: 10.55776/I6685
Duration: 08/01/2024 – 07/01/2027
https://www.fwf.ac.at/en/research-radar/10.55776/I6685

Proteostasis, Metabolism and a Novel Immunodeficiency Syndrome (PROMISE)
CCRI responsible Project Lead: Michael Kraakman (Kaan Boztug group)
Grant from the Austrian Science Fund (FWF), Principal Investigator Project (PAT)
DOI: 10.55776/PAT4663523
Duration: 01/12/2023 – 30/11/2026
https://www.fwf.ac.at/en/research-radar/10.55776/PAT4663523

Disease-associated variants at ARID5B
CCRI responsible Principal Investigator: Davide Seruggia
Grant from the Austrian Science Fund (FWF), Stand-Alone Project
DOI: 10.55776/P36302
Duration: 01/09/2023 – 31/08/2027
https://www.fwf.ac.at/en/research-radar/10.55776/P36302

Lost in translation
CCRI responsible Principal Investigator: Kaan Boztug
Grant from the Austrian Science Fund (FWF), Stand-Alone Project
DOI: 10.55776/P36548
Duration 01/02/2023 – 31/01/2027
https://www.fwf.ac.at/en/research-radar/10.55776/P36548

Harnessing vulnerabilities at SAGA in MYC-driven cancer
CCRI responsible Principal Investigator: Davide Seruggia
Grant from the Austrian Science Fund (FWF), Stand-Alone Project
DOI: 10.55776/P36069
Duration: 01/01/2023 – 31/12/2026
https://www.fwf.ac.at/en/research-radar/10.55776/P36069

CD Laboratory for “Next generation CAR-T cells”
Head of CD Laboratory and Coordinator: Manfred Lehner
Grant from the Christian Doppler Association, Christian Doppler Lab, ID – 345
Duration: 01/11/2019 to 31/10/2026
https://christian-doppler.ccri.at/

Internationally Funded Projects

Elucidating the role of chromosomal copy number variants in neuroblastoma
CCRI responsible Principal Investigator: Florian Halbritter
Coordinator: Anestis Tsakiridis (University of Sheffield, UK)
Grant from Cancer Research UK, Discovery Research
Duration: 01/06/2026 – 31/05/2029

Enhanced International Research on Very Rare Cancers of Paediatric & AYA Age: The Collaborative Observational Study for Pancreatoblastoma and Adrenocortical Carcinoma (Partner4VRT)
CCRI responsible Principal Investigator: Andishe Attarbaschi
Grant from the European Union, EU4Health Work Programme, ID – 101248798
Duration: 01/01/2026 – 31/12/2027
https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/projects-details/

Deciphering neurodegeneration in LCH
CCRI responsible Project Lead: Raphaela Schwentner (Caroline Hutter group)
Grant from the Histiocytosis Association, Conquering the Histiocytic Disorders 2025
Duration: 01/01/2026 – 31/12/2026
https://histio.org/grants/deciphering-neurodegeneration-in-lch/

The prognostic value of circulating tumour DNA and RNA and circulating IGF2BP3 protein in recurrent and refractory Ewing sarcoma: biomarker analysis of the rEECur trial
CCRI responsible Principal Investigator: Eleni Tomazou
Coordinator: Martin McCabe (University of Manchester, UK)
Grant from the Bone Cancer Research Trust, UK
Duration: 22/09/2025 – 21/09/2027

In vivo programming of Ewing sarcoma
CCRI responsible researcher and Awardee: Hana Bernhardova (Supervisor: Eleni Tomazou)
Grant from the Boehringer Ingelheim Fonds (BIF), PhD Fellowship, Germany
Duration: 01/09/2025 – 31/08/2027

Prognostic impact of genome wide copy number study on patients enrolled in the SIOPEN/HR-NBL1 trial
CCRI responsible Principal Investigator: Sabine Taschner-Mandl
Grant from the SIOPEN Association
Duration: 01/06/2025 – 31/05/2027
https://www.siopen.org/news/grant-call-2024-winners

Tumor initiation in familiar SDHb-mutated paraganglioma modeled in human iPSCs-based organoids
CCRI responsible Principal Investigator: Polina Kameneva
Grant from the Paradifference Foundation, UK
Duration: 01/09/2024 – 31/08/2026

European Rare Diseases Research Alliance (ERDERA)
CCRI responsible Principal Investigator: Kaan Boztug
Coordinator: Daria Julkowska (INSERM, France)
Grant from the European Union, HORIZON Work Programme, ID – 101156595
Duration: 01/09/2024 – 31/08/2031

A SIOPEN pragmatic clinical trial to MOnitor NeuroblastomA relapse with LIquid biopsy Sensitive Analysis (MONALISA)
CCRI responsible Principal Investigator and Coordinator: Sabine Taschner-Mandl
Grant from the European Union, HORIZON Work Programme, ID – 101137028
Duration: 01/01/2024 – 31/12/2028
https://cordis.europa.eu/project/id/101137028

European Reference Network on Paediatric Cancer (ERN-PaedCan)
CCRI responsible Principal Investigator and Coordinator: Ruth Ladenstein
Grant from the European Union, EU4Health Work Programme, ID – 101155946
Duration: 01/10/2023 – 30/09/2027
https://paedcan.ern-net.eu/

Developmentally programmed pediatric sarcomas: a versatile platform for drug discovery and molecular precision medicine (SARCOMAkids)
CCRI responsible Principal Investigator: Eleni Tomazou
Grant from the European Union, HORIZON ERC-Consolidator Grant, ID – 101087883
Duration: 01/10/2023 – 31/08/2028
https://cordis.europa.eu/project/id/101087883

International Study for Treatment of Childhood Relapsed ALL 2020 (IntReALL 2020)
CCRI responsible Principal Investigator: Andishe Attarbaschi
Coordinator: Arend von Stackelberg (Charité, Germany)
Grant from the European Commission, HORIZON Work Programme, ID – 101104582
Duration: 01/05/2023 – 30/04/2028
https://cordis.europa.eu/project/id/101104582

Functional Interrogation of Non-coding DNA Sequences in leukemia development and drug resistance (FIND-seq)
CCRI responsible Principal Investigator: Davide Seruggia
Grant from the European Union, H2020 ERC-Starting Grant, ID – 947803
Duration: 01/03/2021 – 28/02/2027
https://cordis.europa.eu/project/id/947803

Comprehensive heatmap for TKI-resistance of mutations in BCR-ABL1 kinase domain
CCRI responsible Principal Investigator: Thomas Lion group
Incyte Corporation – Incyte open calls, ID – 5907191
Duration: 01/01/2019 – 01/04/2027