Research for Better Treatment of Childhood Cancer The Cancer Evolution and Genomics research group at ST. Anna CCRI, led by George Cresswell, investigates how childhood cancer develops and why some patients respond differently to treatments. The scientists analyze how genetic changes evolve in tumors and aim to identify new approaches for better treatments. The goal: […]
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A Light Against Cancer A team of scientists at St. Anna Children’s Cancer Research Institute (St. Anna CCRI) has developed a method to eliminate cancer cells with precision, without harming healthy tissue. Using a light-activatable compound called SBTubA4P, they successfully destroyed tumor cells in an animal model. This promising discovery could one day offer a
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Natural Killer Cells in the Fight Against Neuroblastoma A recently published review in Cancer and Metastasis Reviews highlights promising therapeutic strategies utilizing natural killer (NK) cells to combat neuroblastoma, an aggressive pediatric tumor of the sympathetic nervous system. Researchers from St. Anna Children’s Cancer Research Institute and the Medical University of Vienna emphasize that NK cells play
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Student Applies AI in Cancer Detection and supports St. Anna CCRI (Vienna, 21.08.2024) Alessandro Rodias, a student from the Sir Karl Popper School in Vienna has explored the potential of radiomics in cancer detection. Through his innovative project, he has demonstrated how artificial intelligence (AI) can be applied to analyze radiological images for improved cancer diagnosis.
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From Research to Clinic: St. Anna CCRI’s Pharmacogenomics Symposium St. Anna CCRI hosted its first pharmacogenomics symposium, showcasing the intersection of science and clinical practice in precision oncology. Renowned speakers Dr. Mary Relling and Dr. William Evans explored the impact of genetic data on drug prescription and the importance of international guideline development, as well
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Shining New Light on the Onset of Childhood Cancer Cell mutations can occur during human embryonic development, potentially leading to childhood cancer such as neuroblastoma. Polina Kameneva, recently appointed as Principal Investigator at St. Anna Children’s Cancer Research Institute (St. Anna CCRI), is dedicated to investigating these critical phases. She employs mini-organ cultures and genetic
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Polina Kameneva wins FWF Start Prize (21.06.2024) Yesterday, Polina Kameneva won the prestigious FWF START Prize for her innovative research project. In her project she aims to understand the protective mechanisms of cells at different stages of development, particularly with regard to neuroblastoma. The FWF START Prize provides researchers with a financial basis for carrying out long-term
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Long Night of Research 2024 – An Evening of Innovation and Collaboration in Pediatric Cancer Research The Long Night of Research 2024 was a great success, and we are thrilled with the high turnout of visitors. Under the theme “Innovation through Collaboration,” we were able to introduce numerous interested individuals to the fascinating world of
Innovative stem cell model provides insight into childhood cancer origins Researchers from the University of Sheffield and St. Anna Children’s Cancer Research Institute have created a model designed to investigate the origins of neuroblastoma, a cancer primarily affecting infants and young children. The findings offer hope for the creation of tailored treatments which treat aggressive neuroblastomas
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Eleni Tomazou takes up tenure-track assistant professorship at Medical University Vienna (Vienna, 03.05.24) At the beginning of May, Eleni Tomazou took up a §99.5 assistant professorship in sarcoma biology at the Medical University of Vienna. The scientist has been leading a research group on pediatric sarcomas at St. Anna Children’s Cancer Research Institute (CCRI) with great
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Long Night of Research 2024: Working together in Childhood Cancer Research Join us on Friday, May 24th, from 5-11 p.m. and dive into the world of childhood cancer research! (Vienna, 29.04.24) The Long Night of Research 2024 is approaching and cordially invites you to explore the world of childhood cancer research under the motto “Innovation through
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FWF’s ESPRIT Program supports Research on β-Catenin in Wilms Tumor The Austrian Science Fund’s ESPRIT program has awarded funding to Maud Plaschka’s project focused on exploring β-catenin’s role in Wilms tumor, recognizing the need for innovative research in pediatric oncology. This initiative aims to determine the therapeutic potential of β-catenin inhibitors, addressing a significant gap
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MSCA Postdoctoral Fellowship enables the building of fusion-driven Sarcoma Models Sarcomas, aggressive tumors that primarily affect children and adolescents, are the focus of a new project at St. Anna CCRI. Despite advanced medicine, survival rates of patients with Sarcomas are low and treatment methods are outdated. Strengthened by a prestigious Marie Curie Postdoctoral Fellowship, Ornella Urzì is
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Researchers investigate the control center for maintaining immune cell fitness (Vienna, 14.03.2024) The endoplasmic reticulum in human immune cells is the topic of a current research project at the St. Anna Children’s Cancer Research Institute (CCRI). This highly complex network of membrane structures is where the cells proteins are produced and the quality control processes that
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United Fight Against Osteosarcoma: Innovative T-Cell Therapy Research (Vienna, March 12, 2024) The St. Anna Children’s Cancer Research Institute is at the forefront of a groundbreaking research initiative targeting osteosarcoma, the most prevalent aggressive bone cancer in children and young adults. The project, DART2OS, spearheaded by the Institute of Molecular Pathology (IMP) and supported by the
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International Women’s Day: Spotlight on the Power of Women (Vienna, 8.3.2024) In celebration of International Women’s Day, we proudly highlight the incredible women of St. Anna Children’s Cancer Research Institute, where an inspiring 67% of our dedicated team members are women. Among them stand Principal Investigators Eleni Tomazou and Sabine Taschner-Mandl, whose contributions shape the landscape
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