Breakthrough in Langerhans Cell Histiocytosis Research: Stem Cell Model Paves the Way for New Therapies (Vienna, 16 December 2024) Scientists at St. Anna Children’s Cancer Research Institute (St. Anna CCRI) have achieved a milestone in the study of the rare and complex disease Langerhans Cell Histiocytosis (LCH). Using an innovative model based on induced pluripotent […]
‘Working together’ with Sabine Strehl In today’s biomedical research, interdisciplinary collaboration is essential. While leukemia is the most common childhood cancer, certain subtypes are extremely rare necessitating international studies for comprehensive data collection to understand their pathogenesis and prognostic relevance. Sabine Strehl’s research focuses on unraveling the genetic mechanisms behind leukemia development, emphasizing the importance
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Genetic Defect in Secondary Immune Organs Causes Life-Threatening Infections in Children (Vienna, November 22, 2024) An international team led by Kaan Boztug, MD has identified a new form of a rare disease that affects secondary lymphoid organs, shedding light on the significance of these structures for the human immune system. The discovered genetic defect leads
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Collaboration with Davide Seruggia In biomedicine, collaboration is more than a buzzword—it’s an essential component of advancing our understanding of complex diseases. As technology and scientific knowledge evolve, the scope of research has expanded to include numerous specialized fields, each bringing unique insights and tools. Consequently, biomedicine relies increasingly on interdisciplinary research groups, where scientists
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How to Combat Fungal Infections in Immunocompromised Patients? (Vienna, 17. 10. 2024) A new study from the St. Anna Children’s Cancer Research Institute (St. Anna CCRI) warns of the hidden dangers of invasive fungal infections in immunocompromised patients. The international research team, led by scientists Chantal Lucini, Klára Obrová, and Thomas Lion, has found that
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ESCCA Conference 2024: Advancements in Clinical Cell Analysis Margarita Maurer-Granofszky, researcher of the Dworzak group, was invited to present her research at the ESCCA Conference 2024. In her presentations, she highlighted the importance of detecting minimal/measurable residual disease (MRD) in children with acute myeloid leukemia (AML) and how new technologies like artificial intelligence (AI) can
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New Insights into Risk Factors for a Subtype of Acute Lymphoblastic Leukemia A team around Sabine Strehl and Dagmar Schinnerl has made significant progress in studying a subtype of B-cell acute lymphoblastic leukemia. The research findings, recently published in the Blood Cancer Journal, shed new light on the specific characteristics and risk factors of this
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Resistance is Futile: DOC Fellowship for Cancer Resistance Research Leonie Lehmayer, a dedicated early-career researcher at St. Anna Children’s Cancer Research Institute, has recently been awarded a prestigious DOC Fellowship from the Austrian Academy of Sciences. Her PhD project focuses on studying enhancers and their role in drug resistance and relapse in cancer patients. Many
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Replacing animal testing for Langerhans cell histiocytosis Caroline Hutter’s group at St. Anna CCRI recently received a major grant from the FWF to develop advanced, animal-free therapeutic approaches for the treatment of Langerhans cell histiocytosis (LCH). This rare disease, caused by an excessive accumulation of langerin expressing cells, poses a major challenge, especially for young
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When Acute Lymphoblastic Leukemia (ALL) Transforms (Vienna, 05.04.2024) Acute lymphoblastic leukemia (ALL) is highly treatable. However, for new treatment methods in personalized medicine, subtypes of this leukemia must be studied more thoroughly. A team of researchers from St. Anna Children’s Cancer Research Institute and the University of Padua has now made another step forward in
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The two faces of neutrophils in tumor biology (Vienna, 26.03.2024) Neutrophils are the most common white blood cells and an important component of the immune system. They help in the defense against pathogens and in the healing of injuries. They are also suspected to play a role in tumor development. A team from St. Anna
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Exploring Horizons: SIOPEN Translational Research Meeting in Vienna (Vienna, 31.1.2024) Over the past three days, scientists from leading institutes such as St. Anna CCRI, Charite, Curie, Prinses Maxima Center, University of Leeds and the Vall d’Hebron University Hospital engaged in dynamic discussions on pivotal topics, spanning the realms of Liquid Biopsies, Tumor Biology, and New
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Kaan Boztug in the Spotlight: Pediatric Innovations on “Spontan gefragt” (Vienna 27.12.2023) Tonight at 8:15 pm on Kurier.TV, viewers will have the unique opportunity to delve into the world of pediatric medicine during the science talk show “Spontan gefragt.” The episode features Kaan Boztug, the Scientific Director of St. Anna CCRI, alongside actress Lilian Klebow
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Inaugural International Workshop on Innovative Models for Neuroblastoma Research (Vienna, 15.12.2023) On December 14th and 15th, the St. Anna Children’s Cancer Research Institute proudly hosted the inaugural International Workshop on Innovative Models for Neuroblastoma Research. This groundbreaking event gathered experts from Austria, the UK, the USA, Belgium, and Sweden, all converging at St. Anna CCRI
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35 Years of Pioneering Pediatric Cancer Research: An Anniversary Shaping the Future (Vienna, 05.12.2023) The St. Anna Children’s Cancer Research Institute celebrates 35 years at the forefront of scientific efforts against pediatric cancer. On this anniversary, the institute granted rare insights into its laboratories, showcasing the cutting-edge research that is conducted. Afterwards, the management presented
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Joint Effort to Fast-Track Diagnoses (Vienna, 21.11.2023) Partners from two EU-funded initiatives, the European Joint Program for Rare Diseases (EJPRD) and The European Rare Diseases Research Coordination and Support Action (ERICA), converged at a joint conference in Amsterdam. The joint conference of EJPRD and ERICA served as a critical platform for participants to explore and
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