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Better Therapy Selection for Childhood Leukemia

Better Therapy Selection for Childhood Leukemia Despite decades of optimization of treatment protocols, the prognosis for acute myeloid leukemia in children (pediatric AML, pedAML) remains poor for many patients. A research team from St. Anna Children’s Cancer Research Institute (St. Anna CCRI), the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, […]

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Four Researchers Honored for High-Impact Pediatric Studies

Four Researchers Honored for High-Impact Pediatric Studies The 63rd Annual Meeting of the Austrian Society of Pediatrics and Adolescent Medicine (ÖGKJ) brought together leading researchers under the theme “Together into the Future.” This year’s conference featured comprehensive discussions on the latest advances in pediatric medicine, with plenary sessions focusing on rare diseases, artificial intelligence, and

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Bridging to clinical translation: Professor Kaan Boztug honored for his research on personalized medicine approaches for inborn errors of immunity

Bridging to clinical translation: Professor Kaan Boztug honored for his research on personalized medicine approaches for inborn errors of immunity (Vienna, August 2025) Prof. Dr. med. Kaan Boztug has been awarded the prestigious Novartis Prize for Therapy-Relevant Immunological Research 2025. As a pediatrician and expert in rare diseases of the immune system and blood formation, Boztug

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IGF-1 as the “Ignition Key” for Bone Cancer: Vienna-Based Research Team Unravels Origins of Ewing Sarcoma

IGF-1 as the “Ignition Key” for Bone Cancer: Vienna-Based Research Team Unravels Origins of Ewing Sarcoma A team of scientists led by Heinrich Kovar, Principal Investigator at St. Anna Children’s Cancer Research Institute (St. Anna CCRI) in Vienna, has uncovered a key mechanism in the development of Ewing sarcoma, one of the most aggressive forms

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Networking as a natural consequence of outstanding research …with Florian Halbritter

Networking as a natural consequence of outstanding research …with Florian Halbritter In modern science, collaboration is the key to innovation and breakthroughs, especially in complex research fields such as cancer genomics. Florian Halbritter, head of the “Developmental Cancer Genomics” research group at St. Anna Children’s Cancer Research Institute, exemplifies the importance of this interdisciplinary collaboration

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How collaboration drives innovation… with Florian Grebien

How collaboration drives innovation… with Florian Grebien Collaborations are essential in the world of science. In addition to the exchange of knowledge and technologies, they also offer valuable insights into different cultural and methodological approaches to research. This view is shared by Florian Grebien, Principal Investigator (PI) of the Biology of Pediatric Leukemia Oncoproteins research

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Very Rare Subtype of Childhood Leukemia Characterized

Very Rare Subtype of Childhood Leukemia Characterized A team at the St. Anna Children’s Cancer Research Institute (St. Anna CCRI) has headed an international collaborative study to characterize a very rare subtype of childhood B-cell acute lymphoblastic leukemia. The results, recently published in the journal Leukemia show that patients with this subtype need optimized therapy.

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Breakthrough in Langerhans Cell Histiocytosis Research: Stem Cell Model Paves the Way for New Therapies

Breakthrough in Langerhans Cell Histiocytosis Research: Stem Cell Model Paves the Way for New Therapies (Vienna, 16 December 2024) Scientists at St. Anna Children’s Cancer Research Institute (St. Anna CCRI) have achieved a milestone in the study of the rare and complex disease Langerhans Cell Histiocytosis (LCH). Using an innovative model based on induced pluripotent

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‘Working together’ with Sabine Strehl

‘Working together’ with Sabine Strehl In today’s biomedical research, interdisciplinary collaboration is essential. While leukemia is the most common childhood cancer, certain subtypes are extremely rare necessitating international studies for comprehensive data collection to understand their pathogenesis and prognostic relevance. Sabine Strehl’s research focuses on unraveling the genetic mechanisms behind leukemia development, emphasizing the importance

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Genetic Defect in Secondary Immune Organs Causes Life-Threatening Infections in Children

Genetic Defect in Secondary Immune Organs Causes Life-Threatening Infections in Children (Vienna, November 22, 2024) An international team led by Kaan Boztug, MD has identified a new form of a rare disease that affects secondary lymphoid organs, shedding light on the significance of these structures for the human immune system. The discovered genetic defect leads

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Collaboration with Davide Seruggia

Collaboration with Davide Seruggia In biomedicine, collaboration is more than a buzzword—it’s an essential component of advancing our understanding of complex diseases. As technology and scientific knowledge evolve, the scope of research has expanded to include numerous specialized fields, each bringing unique insights and tools. Consequently, biomedicine relies increasingly on interdisciplinary research groups, where scientists

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How to Combat Fungal Infections in Immunocompromised Patients?

How to Combat Fungal Infections in Immunocompromised Patients? (Vienna, 17. 10. 2024) A new study from the St. Anna Children’s Cancer Research Institute (St. Anna CCRI) warns of the hidden dangers of invasive fungal infections in immunocompromised patients. The international research team, led by scientists Chantal Lucini, Klára Obrová, and Thomas Lion, has found that

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ESCCA Conference 2024: Advancements in Clinical Cell Analysis

ESCCA Conference 2024: Advancements in Clinical Cell Analysis Margarita Maurer-Granofszky, researcher of the Dworzak group, was invited to present her research at the ESCCA Conference 2024. In her presentations, she highlighted the importance of detecting minimal/measurable residual disease (MRD) in children with acute myeloid leukemia (AML) and how new technologies like artificial intelligence (AI) can

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