Zebrafish platform Austria for preclinical drug screening
Background
The Zebrafish platform Austria for preclinical drug screening (ZANDR) was established at the Children´s Cancer Research Institute (CCRI) by the Distel laboratory in 2019 and is a unique platform to phenotypically screen small compounds on zebrafish models of human diseases.
Zebrafish and in particular zebrafish larvae are a well suited vertebrate model system to investigate various human diseases and to perform cost-effective screens for small molecules with therapeutic potential (1). Funded by FFG, we have established a zebrafish-optimized and automated screening platform, which is open to the scientific community. Please contact us, if you are interested in collaboration.
(Reference 1: MacRae CA & Peterson RT (2015), Zebrafish as tools for drug discovery, Nat Rev Drug Discov. Oct;14(10):721-31. Doi: 10.1038/nrd4627
You can find more information here:
www.zandr-ccri.at