News

CLOSER Leukemia General Assembly: Sabine Strehl presents joint work package

CLOSER Leukemia General Assembly: Sabine Strehl presents joint work package (Vienna, 20.11.2023) Sabine Strehl from St. Anna Childrens Cancer Research Institute, recently participated in the CLOSER Leukemia General Assembly in Santiago de Chile, presenting alongside her colleagues Patricia Rubio and Maria Sara Felice from Garrahan Hospital, Buenos Aires. They shared the latest outcomes from their […]

CLOSER Leukemia General Assembly: Sabine Strehl presents joint work package Read More »

VULSK Specialists Immerse in Clinical Trials Training at St. Anna CCRI under TREL Project

VULSK Specialists Immerse in Clinical Trials Training at St. Anna CCRI under TREL Project (Vienna, 17.11.2023) The EU-funded project TREL seeks to bridge gaps in research indicators and treatment outcomes by fostering collaboration, knowledge sharing, and skill development. This week, the St. Anna Childrens Cancer Research Institute warmly welcomed three specialists from Vilnius University Hospital Santaros Klinikos (VULSK)

VULSK Specialists Immerse in Clinical Trials Training at St. Anna CCRI under TREL Project Read More »

Network-based approaches open a new avenue to classify and treat rare diseases

Network-based approaches open a new avenue to classify and treat rare diseases Scientists at CeMM, Max Perutz Labs, and St. Anna Children’s Cancer Research Institute have achieved a significant advancement in the research of rare immune system disorders. Through a network-based approach, they have reclassified approximately 200 rare diseases. Initial comparisons with clinical data already

Network-based approaches open a new avenue to classify and treat rare diseases Read More »

Gene Mutation in the Immune System: Anti-Diabetes Drugs Make Immune Cells More Effective Again

Gene Mutation in the Immune System: Anti-Diabetes Drugs Make Immune Cells More Effective Again (Vienna, 31.08.2023) T cells are an essential component of the immune system – they fight foreign structures such as bacteria and viruses or cancer-related changes in cells. This defense reaction requires energy. Scientists led by the St. Anna Children’s Cancer Research Institute

Gene Mutation in the Immune System: Anti-Diabetes Drugs Make Immune Cells More Effective Again Read More »

“I think there are few things that so many people agree on as that it is good to support St. Anna CCRI!”

“I think there are few things that so many people agree on as that it is good to support St. Anna CCRI!” (Vienna, 28.08.2023) “Science Buster” and molecular biologist Martin Moder in brief: Why he supports the St. Anna Children’s Cancer Research Institute, how he deals with criticism, and what he currently likes doing best!

“I think there are few things that so many people agree on as that it is good to support St. Anna CCRI!” Read More »

Childhood cancer: “New” immune system responds better to therapy

(Vienna, 9.8.2023) Scientists at St. Anna Children’s Cancer Research Institute and the Eberhard Karls University of Tübingen have shown that immunotherapy after stem cell transplantation effectively combats certain nerve tumors in children. Crucially, stem cells from a parent provide children with a new immune system that responds much better to immunotherapies. These results of an early clinical trial were published in the prestigious Journal of Clinical Oncology.

Childhood cancer: “New” immune system responds better to therapy Read More »

St. Anna CCRI welcomes George Cresswell as new Principal Investigator

St. Anna CCRI welcomes George Cresswell as new Principal Investigator (Vienna, 01.08.2023) British bioinformatician George Cresswell has been studying various forms of childhood cancer, especially nephroblastoma, since his student days. As Principal Investigator at St. Anna Children’s Cancer Research Institute, he will turn his attention to the evolutionary biology of cancer cells in an attempt

St. Anna CCRI welcomes George Cresswell as new Principal Investigator Read More »

Sarcoma Awareness Month: exposing an insidious Nemesis

Sarcoma Awareness Month: exposing an insidious Nemesis (Vienna, 27.07.2023) Sarcomas pose a significant challenge, especially for children and adolescents, as the tumors often go undetected and metastasize. At St. Anna Children’s Cancer Research Institute, two research groups are dedicated to studying this tumor. Sarcomas are rare forms of cancer, comprising only two percent of all

Sarcoma Awareness Month: exposing an insidious Nemesis Read More »

“I wish you the best of luck and groundbreaking research results!”

“I wish you the best of luck and groundbreaking research results!” (Vienna, 24.07.2023) Bestselling author Ursula Poznanski in brief: Why she supports the St. Anna Children’s Cancer Research Institute, how she deals with criticism, and what her best decision was! Under the motto of our 35th anniversary “Reaching for the stars”, we interviewed exciting, renowned

“I wish you the best of luck and groundbreaking research results!” Read More »

Automated testing of pediatric cancer therapies

With a novel High-Throughput-Screening method the efficacy of numerous drugs can be tested simultaneously. Researchers are now able to quickly and efficiently assess which substances are effective against certain tumors. A team led by Martin Distel, PhD, and Sabine Taschner-Mandl, PhD, of St. Anna Children’s Cancer Research Institute has now provided the first guide on how to use this method to test the sensitivity of childhood tumors to different drugs in zebrafish models. The study was published in the Journal npj Precision Oncology.

Automated testing of pediatric cancer therapies Read More »

Childhood cancer: Vulnerability in the immune response against metastases discovered

Scientists led by Sabine Taschner-Mandl, PhD, St. Anna Children’s Cancer Research Institute, and Nikolaus Fortelny, PhD, Paris Lodron University of Salzburg, are the first to analyze bone marrow metastases from childhood tumors of the nervous system using modern single-cell sequencing analysis. It turns out that cancer cells prevent cells in their environment from fighting the tumor – a process that could be reversed with medication. The findings were published in the renowned journal Nature Communications.

Childhood cancer: Vulnerability in the immune response against metastases discovered Read More »

Newly discovered genetic defect disrupts blood formation and immune system

Newly discovered genetic defect disrupts blood formation and immune system (Vienna, 21.06.2023) In the quest to find the origin of the puzzling symptoms in four children, researchers from St. Anna Children’s Cancer Research Institute, the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences (ÖAW), and the Medical University of Vienna have discovered

Newly discovered genetic defect disrupts blood formation and immune system Read More »

The first-ever ITCC Scientific Days concluded with big success! 

The first-ever ITCC Scientific Days concluded with big success!  The Innovative Therapies for Children with Cancer (ITCC) conference brought together leading international experts and researchers in pediatric oncology to discuss the latest advancements, challenges, and opportunities in understanding and treating pediatric cancers.  Exciting breakthroughs were discussed, including a novel treatment approach for high-grade gliomas that

The first-ever ITCC Scientific Days concluded with big success!  Read More »

Florian Grebien appointed as new Principal Investigator at St. Anna CCRI

Prof. Florian Grebien, PhD, is eager to understand why some childhood leukemias show poor treatment response and how this can be tackled. To this end, he is now establishing his own team at St. Anna Children’s Cancer Research Institute (St. Anna CCRI). “Prof. Grebien is an outstanding researcher. We have followed his scientific achievements for many years and are very pleased to have been able to recruit him as a Principal Investigator to St. Anna CCRI,” says Prof. Kaan Boztug, MD, Scientific Director of St. Anna CCRI.

Florian Grebien appointed as new Principal Investigator at St. Anna CCRI Read More »