When gene regulation goes wrong: uncovering the origins of leukemia B cell development is a carefully controlled process. Genes must be switched on and off at the right time and in the right amount for healthy immune cells to form. When this precise sequence of events is altered, leukemia can develop instead. In a new […]
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Protein complex formed by ARID5B and its binding partners.
Mechanism of leukemia predisposition unraveled Read More »
Three research grants to strengthen precision medicine for pediatric cancer patients The Vienna Science and Technology Fund (WWTF) has funded three research projects on pediatric cancer in the same funding round—all of them including researchers at St. Anna CCRI. The projects, designed in collaboration with scientists at other Viennese and German institutions, aim to improve
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A SAGA of instability: Without scaffold, a key driver of childhood leukemia falls apart (Vienna, 20.04.2026) – Researchers in the Seruggia group at St. Anna Children’s Cancer Research Institute (St. Anna CCRI) and the CeMM Research Center for Molecular Medicine have uncovered a new way to tackle acute myeloid leukemia (AML) cells in children: Instead of directly targeting
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Emerging Field Grant supports childhood cancer research As part of the excellent=austria initiative, the Austrian Science Fund (FWF) is promoting innovative research collaborations in Austria through its Emerging Fields programme. Over the next five years, selected consortia will work to develop new, highly innovative research fields. Following a competitive international review process focusing on scientific
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Researchers decode cancer’s genetic control panel one DNA letter at a time Scientists in Davide Seruggia’s group at St. Anna Children’s Cancer Research Institute (St. Anna CCRI), together with collaborators at the Broad Institute of MIT and Harvard, have developed CRISPR-Millipede, a new CRISPR-based method that allows researchers to study regulatory DNA sequences at single-nucleotide
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Guiding Stem Cells Step by Step: New Tool Improves Models of Pediatric Cancer Development To study the molecular causes of pediatric cancer, scientists need to recreate complex developmental processes in the lab – an effort that often requires a great deal of trial and error. Scientists in the labs of Florian Halbritter and Davide Seruggia
